Turning Up Gene Expression to Treat Disease / Cell, December 7, 2017 (Vol. 171, Issue 7)

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Published on Dec 11, 2017 at 09:12 pm

In a new study, the therapeutic potential of Cas9-based epigenetic gene activation is explored in mouse models of type I diabetes, acute kidney injury, and muscular dystrophy.

Check out the paper at: http://www.cell.com/cell/fulltext/S0092-8674(17)31247-3.

H.-K. Liao, F. Hatanaka, T. Araoka, P. Reddy, M.-Z. Wu, Y. Sui, T. Yamauchi, M. Sakurai, D. O'Keefe, E. Nunez, et al. (2017). In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation. Cell 171.

And read more great research at http://www.cell.com/cell/home.


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